Non-surgical injectable treatments like Botox, Dysport and Xeomin use a purified botulinum toxin that acts as a neuromodulator to relax the underlying facial muscles and soften the appearance of fine lines and dynamic wrinkles. When injected into the muscle, the botulinum neuromodulator works to prevent excessive muscle contractions, which cause lines and wrinkles to appear over time.
In order to investigate the recent drift of innovation on botulinum neuromodulator (BN), a technology landscape is performed. The structure of botulinum toxin along with formulation, mechanism of actions, applications are discussed in the literature review. The keywords such as “botulinum”, “botulinum production”, “botulinum formulation”, “fermentation”, “botulinum delivery”, “botox” are primarily used to find out the patents from most commonly used databases such as USPTO, WIPO, EPO, PatentLens, IPO.
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